Gestational Diabetes
Diagnosed in women during late stages of pregnancy

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Gestational Diabetes: Diagnosed in women during late stages of pregnancy

Some women develop gestational diabetes during the late stages of pregnancy. Although this form of diabetes usually goes away after the baby is born, a woman who has had it is more likely to develop type 2 diabetes later in life, while the baby is more likely to develop obesity and impaired glucose tolerance and/or diabetes later in life. Unlike type 1 diabetes, gestational diabetes was not caused by a lack of insulin, but by blocking effects of other hormones on the insulin that are produced, a condition referred to as insulin resistance.

The hormones of pregnancy or carbohydrate intolerance cause gestational diabetes; it is diagnose during pregnancy through an oral glucose tolerance test. Between 6 and 9 percent of pregnant women, develop gestational diabetes. The placenta supplies a growing fetus with nutrients and water, as well as produces a variety of hormones to maintain the pregnancy. Some of these hormones (estrogen, cortisol, and human placental lactogen) can have a blocking effect on insulin. This is call contra-insulin effect, which usually begins about 20 to 24 weeks into the pregnancy. Self-care and dietary changes are essential in treatment.

Risk Factors
Any woman can develop gestational diabetes during pregnancy, some of the factors that may increase the risk include the following:

• Obesity.

• Family history of diabetes.

• Having give birth previously to a very large infant, a still birth, or a child with a birth defect.

• Having too much amniotic fluid (polyhydramnios).

• Age Factor - women who are older than 35 are at a greater risk for developing gestational diabetes than younger women.

However, increased glucose in the urine is often included in the list of risk factors; it is not to believe to be a reliable indicator for gestational diabetes.

Complication
Unlike type 1 diabetes, gestational diabetes generally does not cause birth defects. Birth defects usually originate sometime during the first trimester (before the 13th week) of pregnancy. But, the insulin resistance from the contra-insulin hormones produced by the placenta does not usually occur until approximately the 24th week. Women with gestational diabetes generally have normal blood sugar levels during the critical first trimester.

The complications of gestational diabetes are usually manageable and preventable. The key to prevention is careful control of blood sugar levels just as soon as the diagnosis of gestational diabetes is made.

Infants of mothers with gestational diabetes are vulnerable to several chemical imbalances, such as low serum calcium and low serum magnesium levels, but, in general, there are two major problems of gestational diabetes: macrosomia and hypoglycemia.

• Macrosomia
  Macrosomia refers to a baby that is considerably larger than normal. All of the nutrients the fetus receives come directly from the mother's blood. If the maternal blood has too much glucose, the pancreas of the fetus senses the high glucose levels and produces more insulin in an attempt to use this glucose. The fetus converts the extra glucose to fat. Even when the mother has gestational diabetes, the fetus is able to produce all the insulin it needs. The combination of high blood glucose levels from the mother and high insulin levels in the fetus results in large deposits of fat which causes the fetus to grow excessively large.

• Hypoglycemia
  Hypoglycemia refers to low blood sugar in the baby immediately after delivery. This problem occurs if the mother's blood sugar levels have been consistently high, causing the fetus to have a high level of insulin in its circulation. After delivery, the baby continues to have a high insulin level, but it no longer has the high level of sugar from its mother, resulting in the newborn's blood sugar level becoming very low. The baby's blood sugar level is checked after birth, and if the level is too low, it may be necessary to give the baby glucose intravenously.

Treatment
Specific treatment for gestational diabetes will be determined by your physician based on:

• your age, overall health, and medical history

• extent of the disease

• your tolerance for specific medications, procedures, or therapies

• expectations for the course of the disease

• your opinion or preference

Treatment for gestational diabetes focuses on keeping blood glucose levels in the normal range. Treatment may include:

• special diet

• exercise

• daily blood glucose monitoring

• insulin injections

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